Webinar Series - Quantitative Genetics Tools for Mapping Trait Variation to Mechanisms, Therapeutics, and Interventions

The NIDA Center of Excellence in Omics, Systems Genetics, and the Addictome has put together a webinar series, Quantitative Genetics Tools for Mapping Trait Variation to Mechanisms, Therapeutics, and Interventions. The goal of this series is to transverse the path from trait variance to QTL to gene variant to molecular networks to mechanisms to therapeutic and interventions. The target audience for this series are those new to the field of quantitative genetics, so please pass this information on to your trainees or colleagues.

Webinar #1 - Introduction to Quantitative Trait Loci (QTL) Analysis
Webinar #2 – Mapping Addiction and Behavioral Traits and Getting at Causal Gene Variants with GeneNetwork
Webinar #3 – Introduction to expression (e)QTL and their role in connecting QTL to genes and molecular networks
Webinar #4 – From Candidate Genes to Causal Variants—Strategies for and Examples of Identifying Genes and Sequence Variants in Rodent Populations
Webinar #4 – From Candidate Genes to Causal Variants—Strategies for and Examples of Identifying Genes and Sequence Variants in Rodent Populations

Friday, June 26, 2020 10am PDT/ 11am MDT/ 12pm CDT/ 1pm EDT

Goals of this webinar (candidate genes to causal variants):

  • To understand when it is practical or (just as often) not practical to try to "clone" the gene or nucleotide variant modulating trait variants
  • To understand that defining the crucial causal nucleotide variant is usually a bonus and often not for the translational or even mechanistic utility of discoveries.
  • To review new sequence-based methods to identify common and rare variants—the reduced complexity cross and epoch-effects in reference populations

Presented by:
Dr. Rob Williams
Professor and Chair
Department of Genetics, Genomics, and Informatics
University of Tennessee Health Science Center

Link to course material in pdf: [P30_Webinar_on_QTGenes_26Jun2020v3.pdf]
Link to course material in powerpoint pptx: [P30_Webinar_on_QTGenes_26Jun2020v3.pptx]

Webinar #3 – Introduction to expression (e)QTL and their role in connecting QTL to genes and molecular networks

Friday, June 12, 2020 10am PDT/ 11am MDT/ 12pm CDT/ 1pm EDT

Goals of this webinar (QTL to gene/molecular networks):

  • Define eQTL
  • Examine the role of eQTL in the relationship of genes and molecular networks with phenotypic QTL
  • eQTL for co-expression networks

Presented by:
Dr. Laura Saba
Associate Professor
Department of Pharmaceutical Sciences
University of Colorado Anschutz Medical Campus

Webinar flyer (pdf)
Link to course material: [https://github.com/OSGA-OPAR/quant-genetics-webinars/tree/master/2020-06-12]

Webinar #2 – Mapping Addiction and Behavioral Traits and Getting at Causal Gene Variants with GeneNetwork

Friday, May 22nd. 2020 10am PDT/ 11am MDT/ 12pm CDT/ 1pm EDT

Goals of this webinar (QTL to gene variant):

  • Demonstrate mapping a quantitative trait using GeneNetwork (GN)
  • Explore GN tools to identify genes and genetics variants related to a QTL

Presented by:
Dr. Rob Williams
Professor and Chair
Department of Genetics, Genomics, and Informatics
University of Tennessee Health Science Center

Link to course material: [https://github.com/OSGA-OPAR/quant-genetics-webinars/blob/master/2020-05-22/Using_GeneNetwork_22May2020v8.pdf]

Webinar #1 - Introduction to Quantitative Trait Loci (QTL) Analysis

Friday, May 8th, 2020
10am PDT/ 11am MDT/ 12pm CDT/ 1pm EDT

Goals of this webinar (trait variance to QTL):

  • Define quantitative trait locus (QTL)
  • Explain how genome scans can help find QTL

Presented by:
Dr. Saunak Sen
Professor and Chief of Biostatistics
Department of Preventative Medicine
University of Tennessee Health Science Center

Link to course material: [https://github.com/OSGA-OPAR/quant-genetics-webinars/blob/master/2020-05-08/README.md]

Any questions or comments, please contact Laura Saba, Laura.Saba at cuanschutz.edu